Item Number：C3472
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Specification & Item NumberC3472-0010 (10ml), C3472-0020 (20ml)
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Storage Conditions-20ºC
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Conditions Carriagedry ice
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Validity Period (Months)18
Product Introduction
MycoNator™-3 based on ciprofloxacin, a member of the 4-quinolone class, a newer family of the fluroquinolone class, broad-spectrum, bactericidal antibiotics. It is one of several synthetic antibiotics available to prevent, treat and control contamination of cell lines by Mycoplasma species. The mode of action (MOA) of ciprofloxacin inhibits bacterial nuclear DNA synthesis by targeting DNA gyrase (topoisomerase II), an enzyme responsible for growth, repair, and reproduction of bacteria. Specifically, it is responsible for the supercoiling and uncoiling of DNA so that DNA can be twisted in a number of chromosomal domains and seal around an RNA core. Supercoiling of DNA allows the long DNA molecule to fit into the cells. Uncoiling of the DNA is the initiative step for replication, transcription, and repair of the DNA. Therefore, the prolonged inhibition caused by MycoNator™-3 will eventually lead to the death of microorganism.
Since the introduction of echinocandins (i.e., synthetically modified lipopeptides which inhibit the synthesis of β-D-glucan in fungal cell wall) and the broad-spectrum azoles, amphotericin B formulations became less popular in use. However, with its long-proven track record, its place in the anti-fungal armamentarium is still ensured.
Since the introduction of echinocandins (i.e., synthetically modified lipopeptides which inhibit the synthesis of β-D-glucan in fungal cell wall) and the broad-spectrum azoles, amphotericin B formulations became less popular in use. However, with its long-proven track record, its place in the anti-fungal armamentarium is still ensured.
Product Application
MycoNator™-3 based on ciprofloxacin, a member of the 4-quinolone class, a newer family of the fluroquinolone class, broad-spectrum, bactericidal antibiotics. It is one of several synthetic antibiotics available to prevent, treat and control contamination of cell lines by Mycoplasma species.
Production And Quality System
Manufacturing in accordance with cGMP guidelines, in accordance with ISO13485 production standards.
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