In clinical chromosomal analysis, Colcemid exhibits lower cytotoxicity compared to colchicine.
As a microtubule polymerization inhibitor, it arrests mitosis at metaphase by disrupting spindle formation, thereby yielding abundant metaphase cells for karyotyping.
The optimized formulation of Colcemid enhances cytogenetic preparation efficiency and quality, enabling extended chromosomal spreading for improved visualization and analytical precision.